Chlorhexidine should be used with caution in patients with what condition?

Chlorhexidine is an antimicrobial agent commonly used in dental practice for its effectiveness in reducing plaque and gingivitis. However, its use should be approached with caution in patients with kidney disease. This is primarily due to the fact that chlorhexidine can accumulate in the body if the kidneys are not functioning properly, potentially leading to toxicity or adverse effects.

Patients with kidney impairment may have a reduced ability to eliminate chlorhexidine, which can increase the risk of systemic side effects. Therefore, it is crucial to evaluate renal function before using chlorhexidine in these patients and consider alternative treatment options or a modified regimen as needed.

Understanding the implications of kidney disease on medication metabolism and excretion is vital in providing safe and effective dental care.